The question has been closed for the following reason "splat44 won 100.00 µBTC for the best answer." by hansome 20 Mar, 02:20
If all video cards are the same brand, running miner should not be a problem as it should recognize those GPU's. You might have to connect four monitors to each card for running mining client though!
Otherwise, having Radeon and nVidia cards, might cause confusion towards miner client.
If miner client allow mixing GPU brands name card, it's usually require installing proper drivers for example:
Regarless which mining client, including kind of (GPU - all same or mixed), it always best downloading current driver according to your GPU (Drivers listed above)
Unless your system is completely reserved for mining, doing anything else on your system having multiple driver might crash system!
CGminer should let you even if you are mixing AMD and NVIDIA. The NVIDIA cards probably aren't worth the power though unless you sick them on litecoin...
answered 14 Mar, 03:43 Atruk 3.2k●1●10